|
DRUM >
Theses and Dissertations from UM >
UM Theses and Dissertations >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/1903/3596
|
| Title: | Characterization of Electrodeposited Chitosan Films by Atomic Force Microscopy and Raman Spectroscopy |
| Authors: | Dreyer, Erin C |
| Advisors: | Rubloff, Gary W |
| Department/Program: | Material Science and Engineering |
| Type: | Thesis |
| Sponsors: | Digital Repository at the University of Maryland
University of Maryland (College Park, Md.) |
| Keywords: | Engineering, Materials Science (0794)
Engineering, Materials Science (0794)
chitosan; roughness; materials and process characterization; AFM; Raman spectroscopy |
| Issue Date: | 8-May-2006 |
| Abstract: | Chitosan has served as a robust and reproducible scaffold for biological reactions by electrodeposition at specific sites in microfluidic channels. However, its growth and properties are not well understood as a function of deposition parameters. To better understand the materials and process science, in-vitro characterization techniques and post-deposition measurements of air-dried films were performed. AFM images of dried films depicted variable, rough morphology not directly correlated to deposition conditions while hydration increased surface homogeneity. Dry roughness increased logarithmically with thickness supporting growth by nucleation. In-vitro fluorescence images showed fairly smooth distribution of chitosan, whereas dried films were much rougher, indicating non-uniform collapse of structure during drying. Raman spectroscopy revealed the presence of primary amine groups active in biofunctionalization and served as a technique for evaluating the spatial selectivity of chit... |
| URI: | http://hdl.handle.net/1903/3596 |
| Appears in Collections: | Materials Science & Engineering Theses and Dissertations
UM Theses and Dissertations
|
Files in This Item:
| File |
Description |
Size | Format | No. of Downloads |
|---|
| umi-umd-3443.pdf | | 918Kb | Adobe PDF | 661 | View/Open |
|
Show full item record
All items in DRUM are protected by copyright, with all rights reserved.
|
